We report gene expression profiling in the fission yeast Schizosaccharomyces pombe. We performed high-throughput sequencing of RNA isolated from wild-type, erh1?, and ccr4? strains. We find that many meiotic gene containing degradation sequence DSR are expressed in vegetative erh1?, while these meiotic mRNAs do not increase in ccr4?, indicating that Erh1 and Ccr4 target different set of genes during vegetative growth. RNA sequencing in wild-type, erh1? and ccr4? strains. Two biological replicates for erh1? and ccr4?, and one sample for wild-type because we already reported wild-type data previously.