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Expression analysis for nasopharyngeal carcinoma cell lines (5-8F and 6-10B)


ABSTRACT: High metastatic nasopharyngeal carcinoma cell line 5-8F expression patterns against low metastatic nasopharyngeal carcinoma cell line 6-10B. This study was done to screen genes related with metastasis in NPC. The microarray analyses were done in a same batch. 6-10B cells are cultured and harvested at three different time points.

ORGANISM(S): Homo sapiens

SUBMITTER: Zhong-Xi Huang 

PROVIDER: E-GEOD-15903 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray analysis of differentially expressed genes between nasopharyngeal carcinoma cell lines 5-8F and 6-10B.

Li Jia J   Fan Ying Y   Chen Jing J   Yao Kai-Tai KT   Huang Zhong-Xi ZX  

Cancer genetics and cytogenetics 20100101 1


Nasopharyngeal carcinoma (NPC) cell lines 5-8F (high tumorigenic and metastatic) and 6-10B (low tumorigenic and metastatic) are subclones of SUNE1. To address their biological differences, three biologic repeats of expression microarray analysis were performed. Only 60 differently expressed genes were identified between the two cell lines. These genes were randomly distributed on all the chromosomes. Gene ontology analysis showed that most of these genes participated in cellular and metabolic pr  ...[more]

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