Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of human primary macrophages experiencing hypoxia reveals hypoxia inducible factors 1 and 2 are important transcriptional effectors


ABSTRACT: Ischemia exists in many diseased tissues including arthritic joints, atherosclerotic plaques and malignant tumors. Macrophages accumulate in these sites and upregulate genes in response to the hypoxia present. We used microarrays to detail the hypoxia upregulated gene in human primary macrophages. Experiment Overall Design: Primary macrophages were differentiated for 7 days in vitro from human peripheral blood (monocyte-derived macrophages, MDMs) and were subjected to severe hypoxia (< 0.5% O2) or normoxia (20.9% O2) in 5% CO2 humidified multi-gas incubators.

ORGANISM(S): Homo sapiens

SUBMITTER: Hsin-Yu Fang 

PROVIDER: E-GEOD-15949 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2009-10-10 | E-GEOD-12442 | biostudies-arrayexpress
2009-09-12 | E-GEOD-17353 | biostudies-arrayexpress
2015-03-31 | E-GEOD-36507 | biostudies-arrayexpress
2011-04-01 | E-GEOD-22832 | biostudies-arrayexpress
2006-03-08 | GSE2384 | GEO
2014-01-08 | E-GEOD-53893 | biostudies-arrayexpress
2016-01-04 | E-GEOD-70530 | biostudies-arrayexpress
2010-06-11 | E-GEOD-2384 | biostudies-arrayexpress
2009-05-05 | GSE15949 | GEO
2008-06-13 | E-GEOD-4725 | biostudies-arrayexpress