Ontology highlight
ABSTRACT:
ORGANISM(S): Streptomyces avermitilis
SUBMITTER: Jun Chen
PROVIDER: E-GEOD-16892 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
FEMS microbiology letters 20090710 2
In our previous studies, AveI was identified as a negative regulator for avermectin biosynthesis in Streptomyces avermitilis NRRL8165, and the aveI-null mutant of NRRL8165 could produce at least 10-fold more avermectin B1a than its wild-type strain. In order to explore the regulatory mechanism by which aveI affects avermectin biosynthesis, in this study, we performed a global comparative gene expression analysis between aveI deletion mutant 8165DeltaI and its wild-type strain using NimbleGen mic ...[more]