Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Daniel Schubert
PROVIDER: E-GEOD-24507 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lafos Marcel M Kroll Phillip P Hohenstatt Mareike L ML Thorpe Frazer L FL Clarenz Oliver O Schubert Daniel D
PLoS genetics 20110407 4
During growth of multicellular organisms, identities of stem cells and differentiated cells need to be maintained. Cell fate is epigenetically controlled by the conserved Polycomb-group (Pc-G) proteins that repress their target genes by catalyzing histone H3 lysine 27 trimethylation (H3K27me3). Although H3K27me3 is associated with mitotically stable gene repression, a large fraction of H3K27me3 target genes are tissue-specifically activated during differentiation processes. However, in plants it ...[more]