Expression Quantitative Trait Locus (eQTL) Mapping of Stage-specific Gene Expression in Progeny from a type I X III Genetic Cross of Toxoplasma gondii

ABSTRACT: The control of gene expression in Toxoplasma is not well understood. As we and others have shown, this organism does contain bipartite promoters that are sufficient to induce gene expression. This information can be used in downstream experiments to identify proteins that bind to experimentally confirmed cis elements. One of these methods, yeast one-hybrid is currently being employed to identify proteins which bind to the BAG1 and B-NTPase promoter elements. Another powerful method that can be used to identify genomic regions containing controllers of gene expression takes advantage of genetic linkage mapping provided by genetic crosses, called expression quantitative trait locus (eQTL) mapping. In the eQTL approach, one uses gene expression as quantitative traits, or phenotypes, in Q

ORGANISM(S): Toxoplasma gondii

SUBMITTER: Michael Behnke 

PROVIDER: E-GEOD-26558 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress