Unknown,Transcriptomics,Genomics,Proteomics

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Epigenetic regulation of miRNA in CLL [ChIP_hsa_miRNA_v3b]


ABSTRACT: Genome-wide profiling of histone 3 lysine 4 trimethylation is used for identification of microRNA transcriptional start sites. Various cell types allow a broad range detection of putative promoters rather independent of tissue specific expression patterns. These data are used for identification of aberrant epigenetic regulation at the respective regions. 11 samples total: 3 primary B-cell samples (1 chronic lymphocytic leukemia [CLL] and 2 healthy controls), 2 CLL related cell lines -/+ 5-aza-2M-bM-^@M-^Y-deoxycytidine (DAC) treatment (Mec-1, EHEB), T-lymphoid cell line JURKAT, myeloid cell line HL-60, colon cancer cell line HCT-116 wild type and double knock out; H3K4me3 enriched vs. input

ORGANISM(S): Homo sapiens

SUBMITTER: Constance Baer 

PROVIDER: E-GEOD-33305 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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