Trancriptome study in rhesus monkey

ABSTRACT: While the next generation sequencing technology is accelerating the discovery of sites in RNA editing, the strategies to accurately identify the editome, the mechanism by which its profile is maintained and its functional significance remain controversial. Here, 90bp × 2, paired-end, strand-specific, polyA-postive RNA-Seq were performed in 3 rhesus monkey tissues, and 90bp × 2, paired-end, whole exome sequencing was performed in blood cells. Combining genome-wide identification and other quality control in multiple tissues from the same individual, we identified a list of editing sites in coding regions from the rhesus macaque, one of our closest evolutionary relatives. Low-scale verification validated all of these sites and the corresponding levels of editing. The editome in macaque codin

ORGANISM(S): Macaca mulatta

SUBMITTER: Jia-Yu Chen 

PROVIDER: E-GEOD-42857 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress