Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Avi Orr-Urtreger
PROVIDER: E-GEOD-5320 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kedmi Merav M Orr-Urtreger Avi A
Physiological genomics 20060919 2
Studies using mice with beta4 nicotinic acetylcholine receptor (nAChR) subunit deficiency (beta4-/- mice) helped reveal the roles of this subunit in bradycardiac response to vagal stimulation, nicotine-induced seizure activity and anxiety. To identify genes that might be related to beta4-containing nAChRs activity, we compared the mRNA expression profiles of brains from beta4-/- and wild-type mice using Affymetrix U74Av2 microarray. Seventy-seven genes significantly differentiated between these ...[more]