Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Jiradet Gloggnitzer
PROVIDER: E-GEOD-55884 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Gloggnitzer Jiradet J Akimcheva Svetlana S Srinivasan Arunkumar A Kusenda Branislav B Riehs Nina N Stampfl Hansjörg H Bautor Jaqueline J Dekrout Bettina B Jonak Claudia C Jiménez-Gómez José M JM Parker Jane E JE Riha Karel K
Cell host & microbe 20140901 3
Nonsense-mediated mRNA decay (NMD) is a conserved eukaryotic RNA surveillance mechanism that degrades aberrant mRNAs. NMD impairment in Arabidopsis is linked to constitutive immune response activation and enhanced antibacterial resistance, but the underlying mechanisms are unknown. Here we show that NMD contributes to innate immunity in Arabidopsis by controlling the turnover of numerous TIR domain-containing, nucleotide-binding, leucine-rich repeat (TNL) immune receptor-encoding mRNAs. Autoimmu ...[more]