Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of human prostate samples from normal donors and prostate cancer patients


ABSTRACT: This SuperSeries is composed of the following subset Series:; GSE6604: Expression data from Normal Prostate Tissue free of any pathological alteration; GSE6605: Expression data from Metastatic Prostate Tumor; GSE6606: Expression data from Primary Prostate Tumor; GSE6608: Expression data from Normal Prostate Tissue Adjacent to Tumor Experiment Overall Design: Refer to individual Series

ORGANISM(S): Homo sapiens

DISEASE(S): normal

SUBMITTER: Federico Alberto Monzon 

PROVIDER: E-GEOD-6919 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process.

Chandran Uma R UR   Ma Changqing C   Dhir Rajiv R   Bisceglia Michelle M   Lyons-Weiler Maureen M   Liang Wenjing W   Michalopoulos George G   Becich Michael M   Monzon Federico A FA  

BMC cancer 20070412


<h4>Background</h4>Prostate cancer is characterized by heterogeneity in the clinical course that often does not correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can reliably predict which patients are at higher risk of developing metastatic disease. Understanding the differences in the biology of metastatic and organ confined primary tumors is essentia  ...[more]

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