Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Edwin Garcia
PROVIDER: E-MTAB-4590 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Garcia Edwin E Hayden Annette A Birts Charles C Britton Edward E Cowie Andrew A Pickard Karen K Mellone Massimiliano M Choh Clarisa C Derouet Mathieu M Duriez Patrick P Noble Fergus F White Michael J MJ Primrose John N JN Strefford Jonathan C JC Rose-Zerilli Matthew M Thomas Gareth J GJ Ang Yeng Y Sharrocks Andrew D AD Fitzgerald Rebecca C RC Underwood Timothy J TJ
Scientific reports 20160907
New biological tools are required to understand the functional significance of genetic events revealed by whole genome sequencing (WGS) studies in oesophageal adenocarcinoma (OAC). The MFD-1 cell line was isolated from a 55-year-old male with OAC without recombinant-DNA transformation. Somatic genetic variations from MFD-1, tumour, normal oesophagus, and leucocytes were analysed with SNP6. WGS was performed in tumour and leucocytes. RNAseq was performed in MFD-1, and two classic OAC cell lines F ...[more]