Analysis of crystallization data in the Protein Data Bank.

ABSTRACT: The Protein Data Bank (PDB) is the largest available repository of solved protein structures and contains a wealth of information on successful crystallization. Many centres have used their own experimental data to draw conclusions about proteins and the conditions in which they crystallize. Here, data from the PDB were used to reanalyse some of these results. The most successful crystallization reagents were identified, the link between solution pH and the isoelectric point of the protein was investigated and the possibility of predicting whether a protein will crystallize was explored.

SUBMITTER: Kirkwood J 

PROVIDER: S-EPMC4601584 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature