3D genomics across the tree of life reveals condensin II as a determinant of architecture type

ABSTRACT: We investigated genome folding across the eukaryotic tree of life. We find four general manifestations of genome organization at chromosome-scale that each emerge and disappear repeatedly over the course of evolution. The submission represents chromosome-length Hi-C contact maps, architecture type and homolog separation analyses for 26 species across the tree of life, representing all subphyla of chordates, all 7 extant vertebrate classes, and 7 out of 9 major animal phyla, as well as plants and fungi.

ORGANISM(S): Strongylocentrotus purpuratus Arachis hypogaea Drosophila melanogaster Xenopus laevis Notamacropus eugenii Aedes aegypti Cristatella mucedo Pleurobrachia bachei Python bivittatus Hypsibius dujardini Agaricus bisporus Branchiostoma lanceolatum Saccharomyces cerevisiae Homo sapiens Muntiacus muntjak Muntiacus reevesi Caenorhabditis elegans Lethenteron camtschaticum Chiloscyllium punctatum Culex quinquefasciatus Acropora millepora Clonorchis sinensis Ciona intestinalis Gallus gallus Aplysia californica Triticum aestivum Pygocentrus nattereri

PROVIDER: GSE169088 | GEO | 2021/04/23

REPOSITORIES: GEO