Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)
TISSUE(S): Plant Cell, Photosynthetic Cell, Leaf
SUBMITTER: Giulia Friso
LAB HEAD: Giulia Friso c/o Klaas van Wijk's Lab
PROVIDER: PXD002186 | Pride | 2019-04-09
REPOSITORIES: Pride
Nishimura Kenji K Apitz Janina J Friso Giulia G Kim Jitae J Ponnala Lalit L Grimm Bernhard B van Wijk Klaas J KJ
The Plant cell 20150929 10
Clp proteases are found in prokaryotes, mitochondria, and plastids where they play crucial roles in maintaining protein homeostasis (proteostasis). The plant plastid Clp machinery comprises a hetero-oligomeric ClpPRT proteolytic core, ATP-dependent chaperones ClpC and ClpD, and an adaptor protein, ClpS1. ClpS1 selects substrates to the ClpPR protease-ClpC chaperone complex for degradation, but the underlying substrate recognition and delivery mechanisms are currently unclear. Here, we characteri ...[more]