Dataset Information
Quantification of highly homologous Major Urinary Proteins in wild house mice
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Urine
SUBMITTER: 
Viktoria Enk
LAB HEAD: Ebrahim Razzazi-Fazeli
PROVIDER: PXD004642 | Pride | 2016-08-08
REPOSITORIES: Pride
Publications
Regulation of highly homologous major urinary proteins in house mice quantified with label-free proteomic methods.
Molecular bioSystems 20160728 10
Major urinary proteins (MUPs) are highly homologous proteoforms that function in binding, transporting and releasing pheromones in house mice. The main analytical challenge for studying variation in MUPs, even for state-of-the-art proteomics techniques, is their high degree of amino acid sequence homology. In this study we used unique peptides for proteoform-specific identification. We applied different search engines (ProteinPilot™vs. PEAKS®) and protein databases (MUP database vs. SwissProt + ...[more]
