Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
SUBMITTER: Fränze Müller
LAB HEAD: Juri Rappsilber
PROVIDER: PXD007250 | Pride | 2018-01-02
REPOSITORIES: Pride
Items per page: 1 - 5 of 25 |
Journal of the American Society for Mass Spectrometry 20171218 2
Quantitative cross-linking/mass spectrometry (QCLMS) is an emerging approach to study conformational changes of proteins and multi-subunit complexes. Distinguishing protein conformations requires reproducibly identifying and quantifying cross-linked peptides. Here we analyzed the variation between multiple cross-linking reactions using bis[sulfosuccinimidyl] suberate (BS<sup>3</sup>)-cross-linked human serum albumin (HSA) and evaluated how reproducible cross-linked peptides can be identified and ...[more]