Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
SUBMITTER: Mario Oroshi
LAB HEAD: Matthias Mann
PROVIDER: PXD009348 | Pride | 2018-12-07
REPOSITORIES: Pride
Wewer Albrechtsen Nicolai J NJ Geyer Philipp E PE Doll Sophia S Treit Peter V PV Bojsen-Møller Kirstine N KN Martinussen Christoffer C Jørgensen Nils B NB Torekov Signe S SS Meier Florian F Niu Lili L Santos Alberto A Keilhauer Eva C EC Holst Jens J JJ Madsbad Sten S Mann Matthias M
Cell systems 20181205 6
Obesity-related diseases affect half of the global population, and bariatric surgery is one of the few interventions with long-lasting weight loss and cardio-metabolic effects. Here, we investigated the effect of Roux-en-Y gastric bypass surgery on the plasma proteome, hypothesizing that specific proteins or protein patterns may serve as key mediators and markers of the metabolic response. We performed mass spectrometry (MS)-based proteomics on two longitudinal studies encompassing 47 morbidly o ...[more]