Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Permanent Cell Line Cell, Epithelial Cell
SUBMITTER: Yicheng Wang
LAB HEAD: Taroh Kinoshita
PROVIDER: PXD014226 | Pride | 2020-02-17
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
170706_KO.dat | Other | |||
170706_KO.mgf | Mgf | |||
170706_KO.raw | Raw | |||
170706_WT.dat | Other | |||
170706_WT.mgf | Mgf |
Items per page: 1 - 5 of 18 |
Nature communications 20200213 1
Glycosylphosphatidylinositol (GPI)-anchored proteins and glycosphingolipids interact with each other in the mammalian plasma membranes, forming dynamic microdomains. How their interaction starts in the cells has been unclear. Here, based on a genome-wide CRISPR-Cas9 genetic screen for genes required for GPI side-chain modification by galactose in the Golgi apparatus, we report that β1,3-galactosyltransferase 4 (B3GALT4), the previously characterized GM1 ganglioside synthase, additionally functio ...[more]