Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Colon
SUBMITTER: Hikaru Tsuchiya
LAB HEAD: Yasushi Saeki
PROVIDER: PXD016369 | Pride | 2020-02-18
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 14 |
Yasuda Sayaka S Tsuchiya Hikaru H Kaiho Ai A Guo Qiang Q Ikeuchi Ken K Endo Akinori A Arai Naoko N Ohtake Fumiaki F Murata Shigeo S Inada Toshifumi T Baumeister Wolfgang W Fernández-Busnadiego Rubén R Tanaka Keiji K Saeki Yasushi Y
Nature 20200205 7794
The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation of ubiquitylated proteins<sup>1,2</sup>. A number of ubiquitin-related molecules have recently been found to be involved in the regulation of biomolecular condensates or membraneless organelles, which arise by liquid-liquid phase separation of specific biomolecules, including stress granules, nuclear speckles and autophagosomes<sup>3-8</sup>, but it remains unclear whether the proteas ...[more]