Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Toxoplasma Gondii Gt1
SUBMITTER: Oscar Vadas
LAB HEAD: Oscar Vadas
PROVIDER: PXD031816 | Pride | 2023-08-31
REPOSITORIES: Pride
Dos Santos Pacheco Nicolas N Brusini Lorenzo L Haase Romuald R Tosetti Nicolò N Maco Bohumil B Brochet Mathieu M Vadas Oscar O Soldati-Favre Dominique D
Nature microbiology 20220915 11
Members of Apicomplexa are defined by apical cytoskeletal structures and secretory organelles, tailored for motility, invasion and egress. Gliding is powered by actomyosin-dependent rearward translocation of apically secreted transmembrane adhesins. In the human parasite Toxoplasma gondii, the conoid, composed of tubulin fibres and preconoidal rings (PCRs), is a dynamic organelle of undefined function. Here, using ultrastructure expansion microscopy, we established that PCRs serve as a hub for g ...[more]