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Ub E2 enzyme UBE2E1+ pepetide(KEGYES)_HDX-MS

ABSTRACT: The ubiquitin E2 enzyme UBE2E1 is able to catalyse ubiquitination modification of KEGYES/KEGYEE sequence-containing proteins in a manner that does not require an E3 enzyme. Here, we investigate the binding hotspot regions of UBE2E1 with the sequence KEGYES by hydrogen-deuterium exchange mass spectrometry.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Xiangwei Wu

LAB HEAD: Xiangwei Wu

PROVIDER: PXD048115 | Pride | 2024-02-07

REPOSITORIES: Pride

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