Transcriptomics

Dataset Information

0

RNAi of human HeLa cells knocked down for Drosha or DGCR8


ABSTRACT: Anaysis of mRNA changes in HeLa cells following knockdown of Drosha or DGCR8. Drosha is a nuclear RNase III that carries out microRNA (miRNA) processing by cleaving primary microRNA transcript (pri-miRNA). DGCR8 is an essential co-factor of Drosha. Experiment Overall Design: siRNA against Drosha or DGCR8 were trasnfected into HeLa cells. siRNA against GFP was used as a control. Biologically duplicated total RNAs were prepared from HeLa cells, 24 hrs and 48 hrs after siRNA transfection.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Jinju Han 

PROVIDER: E-GEOD-13639 | ArrayExpress | 2009-02-21

SECONDARY ACCESSION(S): GSE13639PRJNA113881

REPOSITORIES: GEO, ArrayExpress

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