Data were imported from their GEO record, which contains no information about which dyes were scanned in which channels. CH1 and CH2 have therefore been used throughout.
ORGANISM(S): Homo sapiens
DISEASE(S): Choriocarcinoma,Seminoma,Teratoma,Yolk Sac Tumor,Premalignant Neoplasia,Normal,Embryonal Carcinoma,Malignant Testicular Germ Cell Tumor
SUBMITTER: Rolf I. Skotheim
REPOSITORIES: GEO, ArrayExpress
Cancer research 20050701 13
Embryonal carcinoma is a histologic subgroup of testicular germ cell tumors (TGCTs), and its cells may follow differentiation lineages in a manner similar to early embryogenesis. To acquire new knowledge about the transcriptional programs operating in this tumor development model, we used 22k oligo DNA microarrays to analyze normal and neoplastic tissue samples from human testis. Additionally, retinoic acid-induced in vitro differentiation was studied in relevant cell lines. We identified genes ...[more]