Transcriptomics

Dataset Information

3

Transcription profiling of human U937T:PLZF-RARa Inducible Cells


ABSTRACT: The PLZF-RARa fusion oncoprotein is overexpressed in the t(11;17) subtype of acute promyelocytic leukemia. Gene expression microarrays were used to identify genes involved in leukemic transformation. We used microarray to detect gene expression changes induced by the PLZF-RARa fusion oncoprotein in the U937 cell line Experiment Overall Design: The U937T:PLZF-RARa cell line was engineered to express PLZF-RARa upon tetracycline removal. PLZF-RARa was induced for 48hr and RNA was extracted and hybridized to Affymetrix HGU133Plus2.0 Chips

ORGANISM(S): Homo sapiens  

SUBMITTER: Kim Lee Rice  

PROVIDER: E-GEOD-18476 | ArrayExpress | 2009-12-05

SECONDARY ACCESSION(S): GSE18476PRJNA120211

REPOSITORIES: GEO, ArrayExpress

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