Transcriptomics

Dataset Information

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Transcription profiling of mouse primary cultures from mouse cornea vs those of the adult and 10-day postnatal mouse cornea to elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells


ABSTRACT: To elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells, the gene expression patterns of these primary cultures from mouse cornea were compared with those of the adult and 10-day postnatal mouse cornea.

ORGANISM(S): Mus musculus  

SUBMITTER: Shukti Chakravarti  

PROVIDER: E-GEOD-1867 | ArrayExpress | 2007-10-31

SECONDARY ACCESSION(S): GSE1867GDS857PRJNA90495

REPOSITORIES: GEO, ArrayExpress

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Publications

Microarray studies reveal macrophage-like function of stromal keratocytes in the cornea.

Chakravarti Shukti S   Wu Feng F   Vij Neeraj N   Roberts Luke L   Joyce Sarah S  

Investigative ophthalmology & visual science 20041001 10


PURPOSE: To elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells, the gene expression patterns of these primary cultures from mouse cornea were compared with those of the adult and 10-day postnatal mouse cornea. METHODS: Murine Genome_U74Av2 arrays (Affymetrix Inc., Santa Clara, CA) were used to elucidate gene expression patterns of adult and postnatal day-10 corneal stroma, keratocytes, fibroblasts, and myofibroblasts. RESUL  ...[more]

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