Transcriptomics

Dataset Information

0

Enhancer-like function for long non-coding RNAs in human


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Ulf Andersson Ørom  

PROVIDER: E-GEOD-23549 | ArrayExpress | 2011-04-12

SECONDARY ACCESSION(S): GSE23549PRJNA131819

REPOSITORIES: GEO, ArrayExpress

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Publications


While the long noncoding RNAs (ncRNAs) constitute a large portion of the mammalian transcriptome, their biological functions has remained elusive. A few long ncRNAs that have been studied in any detail silence gene expression in processes such as X-inactivation and imprinting. We used a GENCODE annotation of the human genome to characterize over a thousand long ncRNAs that are expressed in multiple cell lines. Unexpectedly, we found an enhancer-like function for a set of these long ncRNAs in hum  ...[more]

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