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Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Susanne Mandrup Gordon L Hager Rasmus Siersbaek Anne Loft Myong-Hee Sung Ronni Nielsen Sam John Songjoon Baek
PROVIDER: E-GEOD-27826 | ArrayExpress | 2013-04-03
SECONDARY ACCESSION(S): SRP006001GSE27826PRJNA137905
REPOSITORIES: GEO, ArrayExpress, ENA
Siersbæk Rasmus R Nielsen Ronni R John Sam S Sung Myong-Hee MH Baek Songjoon S Loft Anne A Hager Gordon L GL Mandrup Susanne S
The EMBO journal 20110322 8
Adipogenesis is tightly controlled by a complex network of transcription factors acting at different stages of differentiation. Peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer-binding protein (C/EBP) family members are key regulators of this process. We have employed DNase I hypersensitive site analysis to investigate the genome-wide changes in chromatin structure that accompany the binding of adipogenic transcription factors. These analyses revealed a dramatic and dynami ...[more]