Transcriptomics,Genomics

Dataset Information

0

DNA binding factors shape the mouse methylome at distal regulatory regions.


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE30202: DNA binding factors shape the mouse methylome at distal regulatory regions [BIS_seq] GSE30203: DNA binding factors shape the mouse methylome at distal regulatory regions [ChIP-seq] GSE30204: DNA binding factors shape the mouse methylome at distal regulatory regions [ChIP_chip] GSE30280: DNA binding factors shape the mouse methylome at distal regulatory regions [RNA_seq] Refer to individual Series

ORGANISM(S): Mus musculus  

SUBMITTER: Dimos Gaidatzis  Anne Scholer   Michael B Stadler   Robert Ivanek   Rabih Murr   Lukas Burger   Dirk Schuebeler   Dirk Schubeler   Vijay Tiwari   Florian Lienert   Edward J Oakeley    

PROVIDER: E-GEOD-30206 | ArrayExpress | 2011-12-09

SECONDARY ACCESSION(S): GSE30206PRJNA143959

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications


Methylation of cytosines is an essential epigenetic modification in mammalian genomes, yet the rules that govern methylation patterns remain largely elusive. To gain insights into this process, we generated base-pair-resolution mouse methylomes in stem cells and neuronal progenitors. Advanced quantitative analysis identified low-methylated regions (LMRs) with an average methylation of 30%. These represent CpG-poor distal regulatory regions as evidenced by location, DNase I hypersensitivity, pres  ...[more]

Similar Datasets

2011-12-09 | E-GEOD-30203 | ArrayExpress
2011-12-09 | E-GEOD-30204 | ArrayExpress
2014-01-09 | E-GEOD-53241 | ArrayExpress
2016-07-01 | E-GEOD-71115 | ArrayExpress
2016-07-01 | E-GEOD-71244 | ArrayExpress
| PRJNA143959 | ENA
2011-06-21 | E-GEOD-27827 | ArrayExpress
2013-10-31 | E-GEOD-44737 | ArrayExpress
| PRJNA155097 | ENA
| PRJNA154795 | ENA