Transcriptomics

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Peripheral blood mononuclear cells, control vs. Kashin-Beck Disease


ABSTRACT: Objective: To investigate the differences between the gene expression profiles in peripheral blood mononuclear cells (PBMC) from normal controls and patients with Kashin-Beck disease (KBD). Methods: Twenty KBD patients and 12 normal subjects were selected from a KBD-endemic area and divided into four pairs of KBD vs. control (KBD, n=5 per pair; control, n=3 per pair). RNAs were respectively isolated from KBD PBMCs and normal PBMCs. Gene expression profiles were analyzed by oligonucleotide microarray. Two-condition experiment, control vs. KBD PBM cells. Biological replicates: 4 control replicates, 4 KBD replicates.

ORGANISM(S): Homo sapiens  

SUBMITTER: Xiaoming Wu   M J Lammi  Shuang Wang  Xiong Guo  xiaoming wu 

PROVIDER: E-GEOD-32127 | ArrayExpress | 2011-09-22

SECONDARY ACCESSION(S): GSE32127PRJNA147433

REPOSITORIES: GEO, ArrayExpress

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