Transcriptomics

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Expression data of statin treated HUVEC cells transfected siRNA KLF2 or KLF4.


ABSTRACT: KLF2 and KLF4 are important transcriptional factors in endothelial cells, however their roles in statin treatment has not been elucidated. Here we report the comprehensive change of transcripts of statin treated HUVECs transfected with siRNA KLF2 or KLF4. We used repeated microarray analysis of HUVECs treated with pitavastatin for 4hours. Before statin treatment, cells were transfected with siRNA KLF2 or KLF4. HUVECs were used within the first 6 passages. For studies, HUVECs were cultivated in medium EGM2MV containing pitavastatin at a concentration of 1 micromolar.

ORGANISM(S): Homo sapiens  

SUBMITTER: Takahide Kohro  Youichiro Wada   Tatsuhiko Kodama   Takashi Maejima    

PROVIDER: E-GEOD-32693 | ArrayExpress | 2013-01-01

SECONDARY ACCESSION(S): GSE32693PRJNA146895

REPOSITORIES: GEO, ArrayExpress

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