Transcriptomics

Dataset Information

3

Genome-wide analysis of gene transcription in myocardium of mice transgenically expressing human cardiolipin synthase 1 (hCLS1) in cardiac tissue


ABSTRACT: Analysis of the transcriptome of cardiac tissue from mice transgenically expressing human cardiolipin synthesis. The hypothesis tested was that cardiac specific transgenic expression of cardiolipin synthase alters myocardial lipidomic flux resulting in compensatory metabolic gene transcriptional changes that will attenuate pathological environmental and dietary insults on bioenergetics. Total RNA obtained from cardiac tissue from transgenic cardiac specific expressing human cardiolipin synthase 1 (hCLS1) mouse model at 4 months of age compared to wildtype littermates

ORGANISM(S): Mus musculus  

SUBMITTER: Michael Andrew Kiebish   Michael A Kiebish  Richard W Gross  Xianlin Han 

PROVIDER: E-GEOD-33451 | ArrayExpress | 2011-11-05

SECONDARY ACCESSION(S): GSE33451PRJNA148711

REPOSITORIES: GEO, ArrayExpress

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