Transcriptomics

Dataset Information

7

Epigenetics effects of formaldehyde inhalation exposure


ABSTRACT: We set out to test the hypothesis that formaldehyde inhalation exposure significantly alters miRNA expression profiles within the nasal epithelium of nonhuman primates. Here, cynomolgus macaques were exposed to 0, 2, and 6 ppm formaldehyde for 6 hours/day across two consecutive days. RNA was extracted from the nasal maxilloturbinate region, a direct target of formaldehyde inhalation exposure. Genome-wide miRNA expression levels were assessed using microarrays. Cynomolgus macaques (Macaca fascicularis) were exposed to 0, 2 and 6 ppm formaldehyde for 6 hours/day across two consecutive days using whole body exposure chambers. RNA was extracted from the nasal maxilloturbinate region, a direct target of formaldehyde inhalation exposure. Genome-wide miRNA expression levels were assessed using microarrays.

ORGANISM(S): Macaca fascicularis  

SUBMITTER: James A Swenberg   Lisa Smeester  Benjamin C Moeller  Julia E Rager  Rebecca Fry  Rebecca C Fry  Melanie Doyle-Eisele 

PROVIDER: E-GEOD-34978 | ArrayExpress | 2012-09-01

SECONDARY ACCESSION(S): GSE34978PRJNA151111

REPOSITORIES: GEO, ArrayExpress

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