Transcriptomics

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Exon array analysis of the response to bevacizumab/erlotinib in advanced non-small cell lung cancer


ABSTRACT: In the current study, we used exon arrays and clinical samples from a previous trial (SAKK 19/05) to investigate the expression variations at the exon-level of 3 genes potentially playing a key role in modulating treatment response (EGFR, KRAS, VEGFA). Exon-level biomarkers for the response to targeted therapy bevacizumab/erlotinib were identified in patients with metastatic non-small cell lung cancer Multicenter, prospective, open-label, single-arm, phase II trial.

ORGANISM(S): Homo sapiens  

SUBMITTER: Oliver Gautschi  Richard Cathomas   Lukas Bubendorf   Cornelia Dröge   Daniel Rauch   Francesco Zappa   Susanne Crowe   Florent Baty   Martin Früh   Sacha Rothschild   Miklos Pless   Martin Brutsche   Daniel C Betticher    

PROVIDER: E-GEOD-37138 | ArrayExpress | 2013-07-30

SECONDARY ACCESSION(S): GSE37138PRJNA158417

REPOSITORIES: GEO, ArrayExpress

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