Transcriptomics

Dataset Information

8

Expression Data of Treg and Tconv Cells from FoxP3-GFP Chimeric and FoxP3-ires-GFP B6 and NOD Mice


ABSTRACT: The aim of this study was to quantify the impact of chimeric Foxp3-GFP protein on the Treg cell transcriptional program. Duplicate samples of Tconv (CD3+CD4+GFP-) and Treg (CD3+CD4+GFP+) splenocytes were double-sorted to achieve > 99.0% purity, from 6 weeks old male Foxp3-Fusion-GFP and Foxp3-ires-GFP mice of both B6 and NOD backgrounds. Following cell sorting into Trizol, RNA was purified, labeled and hybridized to Affymetrix arrays.

ORGANISM(S): Mus musculus  

SUBMITTER: CBDM Lab   Diane Mathis  Christophe Benoist  Jaime Darce 

PROVIDER: E-GEOD-37605 | ArrayExpress | 2012-04-26

SECONDARY ACCESSION(S): GSE37605PRJNA162393

REPOSITORIES: GEO, ArrayExpress

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