Genomics

Dataset Information

0

ChIP-seq of the HOXA9 and MEIS1 transcription factors in SEM cells.


ABSTRACT: SEM cells were established from the peripheral blood of a 5-year-old girl in relapse with acute lymphoblastic leukaemia (ALL). SEM cells exhibit the t(4;11) chromosomal rearrangement, which leads to production of the MLL-AF4 fusion protein. Hematopoietic transcription factors including HOXA9 and MEIS1 are highly expressed in ALL. ChIP-seq was performed against HoxA9 and MEIS1 in SEM cells. DNA was enriched by chromatin immunoprecipitation (ChIP) and analyzed by Solexa sequencing.

ORGANISM(S): Homo sapiens  

SUBMITTER: Matthew G Guenther   Lee N Lawton  Richard A Young 

PROVIDER: E-GEOD-38339 | ArrayExpress | 2012-05-31

SECONDARY ACCESSION(S): GSE38339SRP013443PRJNA167740

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

2012-05-31 | E-GEOD-38338 | ArrayExpress
| PRJNA385359 | ENA
2017-06-14 | PXD004192 | Pride
2015-12-17 | E-GEOD-74812 | ArrayExpress
2013-07-11 | E-GEOD-48704 | ArrayExpress
2011-01-26 | E-GEOD-26014 | ArrayExpress
| GSE50645 | GEO
| GSE68643 | GEO
| GSE74566 | GEO
2015-01-01 | E-GEOD-50645 | ArrayExpress