Dataset Information


A549 cells before/after NME2 induction

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Vinod Kumar Yadav  

PROVIDER: E-GEOD-40433 | ArrayExpress | 2014-08-04



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Promoter-proximal transcription factor binding is transcriptionally active when coupled with nucleosome repositioning in immediate vicinity.

Yadav Vinod Kumar VK   Thakur Ram Krishna RK   Eckloff Bruce B   Baral Aradhita A   Singh Ankita A   Halder Rashi R   Kumar Akinchan A   Alam Mohammad Parwez MP   Kundu Tapas K TK   Pandita Raj R   Pandita Tej K TK   Wieben Eric D ED   Chowdhury Shantanu S  

Nucleic acids research 20140731 15

Previous studies have analyzed patterns of transcription, transcription factor (TF) binding or mapped nucleosome occupancy across the genome. These suggest that the three aspects are genetically connected but the cause and effect relationships are still unknown. For example, physiologic TF binding studies involve many TFs, consequently, it is difficult to assign nucleosome reorganization to the binding site occupancy of any particular TF. Therefore, several aspects remain unclear: does TF bindin  ...[more]

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