Dataset Information


Spirodiclofen resistance in the spider mite Tetranychus urticae

ABSTRACT: The goal of our microarray experiments was to compare the gene expression profile of two spirodiclofen resistant spider mite strains (SR-VP and SR-TK) with that of a susceptible spider mite strain (LS-VL) 5 samples were analyzed: 3 biological replicates for SR-VP, 2 biological replicates for SR-TK

ORGANISM(S): Tetranychus urticae  

SUBMITTER: Wannes Dermauw   Thomas Van Leeuwen  Peter Demaeght 

PROVIDER: E-GEOD-43538 | ArrayExpress | 2013-06-26



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Molecular analysis of resistance to acaricidal spirocyclic tetronic acids in Tetranychus urticae: CYP392E10 metabolizes spirodiclofen, but not its corresponding enol.

Demaeght Peter P   Dermauw Wannes W   Tsakireli Dimitra D   Khajehali Jahangir J   Nauen Ralf R   Tirry Luc L   Vontas John J   Lümmen Peter P   Van Leeuwen Thomas T  

Insect biochemistry and molecular biology 20130321 6

Spirodiclofen is one of the most recently developed acaricides and belongs to the new family of spirocyclic tetronic acids (ketoenols). This new acaricidal family is an important chemical tool in resistance management strategies providing sustainable control of spider mites such as Tetranychus urticae. Spirodiclofen targets lipid biosynthesis mediated by direct inhibition of acetyl coenzyme A carboxylase (ACCase). In this study, we investigated two genetically distant spider mite strains with hi  ...[more]

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