Transcriptomics

Dataset Information

4

Preimplantation Factor Effect on Endometrial and Decidual Cells


ABSTRACT: Embryos secrete preimplantation factor (PIF), a peptide present in maternal circulation during viable pregnancy. We compared downstream synthetic PIF effect on gene expression in non-pregnant Human Endometrial Stromal Cell (HESC) and First Trimester Decidual cell (FTDC) culture to mimic the maternal intrauterine environment during embryo implantation and trophoblast invasion. Cells were cultured in triplicate with and without synthetic PIF for 24 hours. Cultured cells were then pooled for chip analysis. Altered gene expression relative to controls was assessed by Affymetrix microarray

ORGANISM(S): Homo sapiens  

SUBMITTER: S J Huang   Eytan R Barnea  Michael J Paidas  Christina Maria Duzyj  Lellean Jebailey  Christina M Duzyj  Jack Annunziato  Michael Romano 

PROVIDER: E-GEOD-46326 | ArrayExpress | 2013-06-21

SECONDARY ACCESSION(S): GSE46326PRJNA209047

REPOSITORIES: GEO, ArrayExpress

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