Transcriptomics

Dataset Information

3

Mouse ureter: wild type vs miR-143/145 knock out


ABSTRACT: mRNA profiling of mouse ureters comparing wild-type ureter vs. ureters from mice having whole body deletion of miR-143 and miR-145 which results in abnormal ureter peristalsis and hydronephrosis We used microarrays to detail the global program of gene expression in wild-type and miR-143/145-deficient ureters which revealed dysregulation of genes linked to smooth muscle morphology and function. Two condition experiment: wild type vs miR-143/145 KO; biological replicates: individual mice - 2 wild type, 2 mutant. One replicate per array.

ORGANISM(S): Mus musculus  

SUBMITTER: R A Gomez   Silvia Medrano  Roberto Gomez  Maria S Sequeira-Lopez 

PROVIDER: E-GEOD-58274 | ArrayExpress | 2014-10-08

SECONDARY ACCESSION(S): GSE58274PRJNA251871

REPOSITORIES: GEO, ArrayExpress

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