Transcriptomics

Dataset Information

300

Defining soma-specific/enriched and germline-specific/enriched transcripts


ABSTRACT: To define what genes are predominantly or specifically expressed in either soma or germline in C. elegans adults, total RNA was extracted from germline-less glp-4 mutant animals or from dissected gonads, respectively. Total RNA sequencing was peformed in duplicates. Four samples in total.

ORGANISM(S): Caenorhabditis elegans  

SUBMITTER: Dimos Gaidatzis   Jane Wright  Rafal Ciosk 

PROVIDER: E-GEOD-62857 | ArrayExpress | 2015-01-08

SECONDARY ACCESSION(S): GSE62857SRP049412PRJNA265847

REPOSITORIES: GEO, ArrayExpress, ENA

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Publications

Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes.

Arnold Andreas A   Rahman Md Masuder MM   Lee Man Chun MC   Muehlhaeusser Sandra S   Katic Iskra I   Gaidatzis Dimos D   Hess Daniel D   Scheckel Claudia C   Wright Jane E JE   Stetak Attila A   Boag Peter R PR   Ciosk Rafal R  

Nucleic acids research 20141105 21


The cold shock domain is one of the most highly conserved motifs between bacteria and higher eukaryotes. Y-box-binding proteins represent a subfamily of cold shock domain proteins with pleiotropic functions, ranging from transcription in the nucleus to translation in the cytoplasm. These proteins have been investigated in all major model organisms except Caenorhabditis elegans. In this study, we set out to fill this gap and present a functional characterization of CEYs, the C. elegans Y-box-bind  ...[more]

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