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Microarray analysis of gene expression profiles in human neuroblastoma SH-SY5Y cells exposed to norephedrine

ABSTRACT: To reveal the molecular mechanism underling necrotic neuronal cell death caused by norephedrine, we examined alteration of gene expression profile during norephedrine exposure in human neuroblastoma SH-SY5Y cells. The alteration of gene expression during norephedrine exposure (3 mM, 0,2 and 6 hours) in differentiated SH-SY5Y cells was examined.

ORGANISM(S): Homo sapiens

SUBMITTER: Takeshi Funakoshi

PROVIDER: E-GEOD-67643 | ArrayExpress | 2015-04-08

SECONDARY ACCESSION(S): GSE67643PRJNA280526

REPOSITORIES: GEO, ArrayExpress

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Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling

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2013-06-01 | E-GEOD-43368 | ArrayExpress

Transcription profiling of human human neuroblastoma SH-SY5Y cells identifies molecular effectors of unconjugated bilirubin

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Project description:Recombinant PGRN and GRN peptides were used to treat fully differentiated SH-SY5Y cells. Post-treatment cells were lysed and used for RNA Seq using the ion-Torrent proton platform. Results were validated using real time PCR.

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Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y.

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2015-11-05 | E-GEOD-74673 | ArrayExpress

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2010-12-22 | E-GEOD-21298 | ArrayExpress

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Project description:RNAseq to assess changes in transcript abundance upon knockdown of the RNA-binding protein Unkempt in human SH-SY5Y cell lines.

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