Transcription profiling of chicken jejuna in a time series after orally infection with Salmonella
ABSTRACT: RNA was extracted form chicken jejuna at 0.33,1, 2, 4, 8, 12 and 21 days post-infection, in orally infected (1.10^5 Salmonella ) and control chickens. NOTE: Normalization is performed separately! on control and infected chickens, because the objective was to investigate differences in development.
<h4>Background</h4>Not much is known about the effect of Salmonella enteritidis on changes in the developmental processes occurring in the intestine of young chicken. Therefore we investigated the correlation of intestinal gene expression patterns with the severity of systemic Salmonella infections.<h4>Methods</h4>The number of Salmonella colony forming units (CFUs) in the liver of infected chicken were plotted against the average intestinal expression profiles of previously identified gene expr ...[more]
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