Transcriptomics

Dataset Information

949

Transcription profiling of Aspergillus fumigatus Af293 after temperature shifting


ABSTRACT: Experimental factor: Time after the temperature shift from 30C to 37C or 30C to 48C. Conidia (5x106 /ml) from Aspergillus fumigatus Af293 were incubated in the CM medium for germination (~ 17 hrs) at 30C. The culture was transferred to a water bath of 37C or 48C for continued growth. Samples were taken after the defined time (i.e. 0, 15, 30, 60, 120, and 180 min.).

INSTRUMENT(S): Scanning hardware

ORGANISM(S): Aspergillus fumigatus  

SUBMITTER: H. Stanley Kim  

PROVIDER: E-MEXP-332 | ArrayExpress | 2005-05-15

REPOSITORIES: ArrayExpress

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Publications

Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model.

Do Jin Hwan JH   Yamaguchi Rui R   Miyano Satoru S  

BMC genomics 20090708


BACKGROUND: The thermotolerance of Aspergillus fumigatus plays a critical role in mammalian and avian infections. Thus, the identification of its adaptation mechanism to higher temperature is very important for an efficient anti-fungal drug development as well as fundamental understanding of its pathogenesis. We explored the temporal transcription regulation structure of this pathogenic fungus under heat shock conditions using the time series microarray data reported by Nierman et al. (Nature 20  ...[more]

Publication: 1/2

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