Transcriptomics

Dataset Information

242

Transcription profiling by array of the progestin drospirenone and in mixtures with progesterone in brain and ovary of female zebrafish


ABSTRACT: The commercially available zebrafish (Danio rerio) gene expression microarray (4x44K format, Agilent G2519F-026437) was used to characterise the changes in gene expression levels in the ovary and brain of adult female zebrafish after exposure to 55, 553 and 5442 ng/L DRS for 14 days. Also, the transcriptional response in the brain of adult female zebrafish was characterised after exposure to mixtures of DRS and P4 at concentrations of 27+0.8, 277+8, 3119+123 (ng/L), respectively. This study was designed to achieve an understanding of the mode of action of DRS and steroid mixtures in zebrafish.

ORGANISM(S): Danio rerio  

SUBMITTER: Karl Fent   Leda Mirbahai   Geraldine Chew   Sara Castiglioni   Sara Zucchi  

PROVIDER: E-MTAB-2077 | ArrayExpress | 2014-06-04

REPOSITORIES: ArrayExpress

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