Transcriptomics

Dataset Information

0

Transcriptome of developing testes from the African malaria mosquito Anopheles gambiae


ABSTRACT: Spermatogenesis is a highly complex developmental process, during which diploid germline stem cells are transformed into motile haploid spermatozoa. The process involves a precisely regulated action of a large number of genes, making the testes the most distinct tissue within the body. Testis transcriptome has been analysed in several groups of animals, but never systematically studied in mosquitoes. This dataset, consisting of the transcriptome of the developing testes from late larvae and early pupae of the African malaria mosquito, Anopheles gambiae, closes the existing gap.

INSTRUMENT(S): 454 GS FLX

ORGANISM(S): Anopheles gambiae  

SUBMITTER: Jaroslaw Krzywinski  

PROVIDER: E-MTAB-3264 | ArrayExpress | 2016-01-21

SECONDARY ACCESSION(S): ERP009392

REPOSITORIES: ArrayExpress, ENA

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Publications

Dosage Compensation in the African Malaria Mosquito Anopheles gambiae.

Rose Graham G   Krzywinska Elzbieta E   Kim Jan J   Revuelta Loic L   Ferretti Luca L   Krzywinski Jaroslaw J  

Genome biology and evolution 20160118 2


Dosage compensation is the fundamental process by which gene expression from the male monosomic X chromosome and from the diploid set of autosomes is equalized. Various molecular mechanisms have evolved in different organisms to achieve this task. In Drosophila, genes on the male X chromosome are upregulated to the levels of expression from the two X chromosomes in females. To test whether a similar mechanism is operating in immature stages of Anopheles mosquitoes, we analyzed global gene expres  ...[more]

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