Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yolanda Espinosa-Parrilla
Alicia Gallego
PROVIDER: E-MTAB-3617 | ArrayExpress | 2016-04-03
REPOSITORIES: ArrayExpress
Gallego Alicia A Melé Marta M Balcells Ingrid I García-Ramallo Eva E Torruella-Loran Ignasi I Fernández-Bellon Hugo H Abelló Teresa T Kondova Ivanela I Bontrop Ronald R Hvilsom Christina C Navarro Arcadi A Marquès-Bonet Tomàs T Espinosa-Parrilla Yolanda Y
PloS one 20160422 4
microRNAs are crucial post-transcriptional regulators of gene expression involved in a wide range of biological processes. Although microRNAs are highly conserved among species, the functional implications of existing lineage-specific changes and their role in determining differences between humans and other great apes have not been specifically addressed. We analyzed the recent evolutionary history of 1,595 human microRNAs by looking at their intra- and inter-species variation in great apes usi ...[more]