Transcriptomics

Dataset Information

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Transcription profiling of human pleural mesothelioma versus parietal and visceral pleura


ABSTRACT: Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

TISSUE(S): Pleura Viscerale, Pleural Plaque, Pleural Mesothelioma, Pleura Parietale, Pleura

DISEASE(S): Na,Papillary Serous Adenocarcinoma,Mesothelioma,Normal

SUBMITTER: Endre Anderssen  

PROVIDER: E-MTAB-47 | ArrayExpress | 2009-01-01

REPOSITORIES: ArrayExpress

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Publications

Hidden treasures in "ancient" microarrays: gene-expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue.

Kerkentzes Konstantinos K   Lagani Vincenzo V   Tsamardinos Ioannis I   Vyberg Mogens M   Røe Oluf Dimitri OD  

Frontiers in Oncology 20140929


OBJECTIVE: Novel statistical methods and increasingly more accurate gene annotations can transform "old" biological data into a renewed source of knowledge with potential clinical relevance. Here, we provide an in silico proof-of-concept by extracting novel information from a high-quality mRNA expression dataset, originally published in 2001, using state-of-the-art bioinformatics approaches. METHODS: The dataset consists of histologically defined cases of lung adenocarcinoma (AD), squamous (SQ)  ...[more]

Publication: 1/2

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