Transcriptomics

Dataset Information

17

RNA-seq of breast milk-derived exosomes from type 1 diabetic mothers compared to healthy controls


ABSTRACT: The breast milk plays a crucial role in shaping the initial intestinal microbiota and mucosal immunity of the infant. Interestingly, breastfeeding has proven to be protective against the early onset of immune-mediated diseases including type 1 diabetes (T1D). Studies have shown that exosomes from human breast milk (HM) are enriched in immune-modulating miRNAs suggesting that exosomal miRNAs transferred to the infant could play a critical role in the development of the infant’s immune system. In this study, we extracted exosome exosomal microRNAs (exomiRs) from breast milk of type 1 diabetic and healthy lactating mothers, in order to identify any differences in the exomiR content between the two groups

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo Sapiens

DISEASE(S): Normal,Type I Diabetes Mellitus

SUBMITTER: Flemming Pociot  

PROVIDER: E-MTAB-7336 | ArrayExpress | 2019-08-01

SECONDARY ACCESSION(S): ERP111674

REPOSITORIES: ArrayExpress, ENA

Dataset's files

Source:
Action DRS
E-MTAB-7336.idf.txt Idf
E-MTAB-7336.idf.txt_original Idf
E-MTAB-7336.processed.1.zip Processed
E-MTAB-7336.sdrf.txt Txt
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