Transcriptomics

Dataset Information

0

CLIP-seq analysis of C.elegans MINA-1::GFP transgenic animals.


ABSTRACT: Analysis to determine which mRNAs are specifically associated with MINA-1 protein.

INSTRUMENT(S): Illumina Genome Analyzer IIx

ORGANISM(S): Caenorhabditis elegans  

SUBMITTER: Michael O Hengartner  Luca Ducoli     

PROVIDER: E-MTAB-7420 | ArrayExpress | 2019-02-08

SECONDARY ACCESSION(S): ERP112306

REPOSITORIES: ArrayExpress, ENA

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Publications


Post-transcriptional control of mRNAs by RNA-binding proteins (RBPs) has a prominent role in the regulation of gene expression. RBPs interact with mRNAs to control their biogenesis, splicing, transport, localization, translation, and stability. Defects in such regulation can lead to a wide range of human diseases from neurological disorders to cancer. Many RBPs are conserved between Caenorhabditis elegans and humans, and several are known to regulate apoptosis in the adult C. elegans germ line.  ...[more]

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